Methotrexate tablet is a drug indicated for the treatment of rheumatoid arthritis and severe psoriasis that does not respond to other treatments.In addition, methotrexate is also available as an injection, used in chemotherapy to treat cancer.
This remedy is available as a pill or injection and can be found in pharmacies with the names Tecnomet, Enbrel and Endofolin, for example.
- Methotrexate as tablets is indicated for the treatment of rheumatoid arthritis because it has effects on the immune system.
- Decreasing inflammation.
- Noting its action from the 3rd week of treatment.
- In the treatment of psoriasis.
- Methotrexate decreases the proliferation and inflammation of skin cells.
- And its effects are noticed 1 to 4 weeks after the start of treatment.
Injectable methotrexate is used to treat severe psoriasis and the following types of cancer:
Dosages for each diet should be adjusted gradually for optimal response, but should not exceed a total weekly dose of 20 mg.
The recommended oral dose is 10 to 25 mg per week, up to an adequate response or, alternatively, 2.5 mg, every 12 hours, in three doses.
The doses of each regimen can be gradually adjusted for an optimal clinical response, avoiding exceeding the dose of 30 mg per week.
For severe psoriasis, where injectable methotrexate is used, a single dose of 10 to 25 mg per week should be administered until an adequate response is obtained.Learn how to identify symptoms of psoriasis and essential care.
The therapeutic dose range of methotrexate for oncology indications is very wide, depending on the type of cancer, body weight and patient conditions.
The most common side effects that can occur during treatment with methotrexate tablets are severe headache, stiff neck, vomiting, fever, redness of the skin, increased uric acid and reduced sperm count, onset of mouth ulcers., inflammation of the tongue and gums, diarrhea, decreased number of white blood cells and platelets, renal failure and pharyngitis.
Methotrexate tablet is indicated for contrast in patients allergic to methotrexate or any of the formulation components, pregnant women, lactating women, people with weakened immune systems, severe hepatic or renal dysfunction and changes in blood cells, such as a decrease in the number of white blood cells, red blood cells and platelets.