Leukocystic vascularitis, also known as hypersensitivity vascularitis or small vessel vascularitis, is an inflammation of the blood vessels that can occur as a result of inflammation, infections or autoimmune diseases, resulting in red spots mainly in the legs, thighs and abdominal area.
Diagnosis of this type of vascularitis is made taking into account the symptomatology presented by the person and the results of laboratory tests that the doctor may request; In most cases, symptoms of leukodocyclástica vascularitis go away within a few months, however it may be necessary to use certain medications such as antihistamines or corticosteroids depending on the severity of vascularitis.
- This type of vascularitis can have several causes and is usually linked to factors that promote changes in the immune system; in fact.
- It is believed that the symptoms of leukocystic vascularitis are due to the formation of immunocomplejos in small blood vessels that cause inflammation.
Thus, the main causes related to the development of this type of vascularitis are:
Diagnosis of leukocytactic vascularitis is made by the family doctor, angiologist, rheumatologist or dermatologist by initial assessment of the signs and symptoms presented by the person; In addition, your doctor is invited to perform laboratory tests to help make differential diagnosis, such as blood formula, VSH, liver and kidney tests, and urine tests.
To confirm the diagnosis, your doctor recommends a biopsy of the lesion so that a microscopic evaluation of the tissue can be performed, mainly within 24 to 48 hours after the onset of the first signs and symptoms.Understand how the biopsy should be performed.
Os sintomas da vasculite leucocitoclástica estão relacionadas com a deposição de imunocomplexos nos vasos sanguíneos, que são estruturas formadas por anticorpos, produzidos como consequência do processo inflamatório, e antígenos circulantes. Após a formação dos imunocomplexos e deposição nos vasos, são ativados fatores relacionados com a atividade do sistema imunológico, o que leva ao aparecimento dos sintomas, sendo os principais:
These symptoms are most common in the legs, thighs, buttocks and lower abdomen, in addition, in the most severe cases, systemic symptoms such as fever, un apparent weight loss, muscle pain, blood in the urine or stool and increased abdomen.volume, for example, can be noticed, it is important in these cases to consult a doctor so that the diagnosis can be made and the need to initiate the treatment evaluated.
Look for other signs and symptoms of vascularitis
In most cases of leukocyclastic vascularitis, the symptoms usually disappear without any treatment, but it is important that the cause be identified since strategies to prevent a new episode of vascularitis may be indicated, such as stopping the medication or reducing the consumption of certain food, if vascularitis is related to drug or food allergies Like what.
Em outros casos, quando os sintomas não desaparecem com o tempo ou quando surgem sintomas sistêmicos, o médico pode indicar o uso de alguns medicamentos com o objetivo de evitar a progressão da vasculite e promover a melhora da pessoa, podendo ser recomendado nesses casos o uso de anti-histamínicos ou corticoides, além de ser indicado repouso e elevação das pernas.