Topiramate is an anti-seizure drug known commercially as Topamax, which acts on the central nervous system, stabilizes mood and protects the brain.This medicine is indicated for the treatment of epilepsy in adults and children, for the treatment of seizures associated with Lennox-Gastaut syndrome.and for the prophylactic treatment of migraine.
Topiramate can be purchased in pharmacies, for a price of about 60 to 300 reais, depending on the dose, the size of the package and the brand of the drug, and there is also the possibility to choose the generic.
- Treatment should be initiated at a low dose.
- Which should be gradually increased.
- Until the appropriate dose is reached.
The minimum effective dose is 200 mg per day, up to 1600 mg per day, which is considered the maximum dose.Treatment should be started with 25 to 50 mg, administered at night, for one week.Then, at intervals of 1 or 2 weeks, the dose should be increased from 25 to 50 mg / day and divided into two doses.
For children over 2 years, the recommended daily dose is 5 to 9 mg /kg per day, divided into two administrations.
When other antiepileptic drugs are removed from the treatment plan, to maintain topiramate treatment alone, consideration should be given to the effects it may have on crisis control, advising, if possible, the gradual discontinuation of prior treatment.
In children over 2 years, the initial dose varies from 0.5 to 1 mg / kg per day at night for one week, then the dose should be increased from 0.5 to 1 mg / kg daily, at intervals of 1 to 2 weeks, divided into two administrations.
Treatment should be initiated at 25 mg at night for one week, increasing this dose from 25 mg / day, once a week, to a maximum of 100 mg / day, divided into two administrations.
Topiramate should not be used by people with hypersensitivity to the components of the formula, in pregnant women or women who suspect they may be pregnant.
Some of the more common side effects that can occur during treatment with topiramate are drowsiness, dizziness, fatigue, irritability, weight loss, slow thinking, tingling, double vision, abnormal coordination, nausea, nystagmus, lethargy, anorexia, slurred speech. , blurred vision, decreased appetite.