Dent’s disease is a rare genetic problem that affects the kidneys, resulting in the removal of more proteins and minerals in the urine, which can lead to frequent kidney stones or other more serious problems, such as kidney failure.
Dent’s disease is generally more common in men, but it can also occur in women with milder symptoms.
- Dent’s disease is incurable.
- But there are some treatments that help reduce symptoms and prevent injuries that lead to the development of more serious kidney problems.
The main symptoms of Dent’s disease are
These symptoms usually appear during childhood and get worse over time, especially when treatment is not done correctly.
In addition, Dent’s disease can also be identified in the urine test when there is an exaggerated increase in the amount of protein or calcium, without apparent cause.
Treatment of Dent’s disease should be guided by a nephrologist and generally aims to reduce patients’ symptoms by ingestion of diuretics, such as metolazone or indapamide, which prevent excessive mineral removal, preventing the appearance of kidney stones.
However, as the disease progresses, other problems, such as kidney failure or weakening of bones, may occur, requiring specific treatment, ranging from vitamin intake to dialysis.