TGO and TGP, also known as transaminases, are enzymes that are normally dosed to evaluate liver health. TGO, known as oxalacetic transaminase or AST (aspartate aminotransferralse) occurs in several tissues, such as the heart, muscles and liver, within liver cells.
Thus, when there is an increase in GOT levels only, it is common to relate to another situation that is not related to the liver, since in the case of liver damage, the injury must be more extensive for liver cells to rest. and lead to the release of TGO into the bloodstream.
- On the other hand.
- TGP.
- Known as pyruvic transaminase or ALT (alanine aminotransferables).
- Occurs exclusively in the liver and therefore.
- If this organ changes.
- There is an increase in the circulating amount in the blood.
- Learn more about TGP.
TGO and TGP values may vary by laboratory, however, in general, the values considered normal in the blood are:
Although TGO and TGP are considered liver markers, these enzymes can also be produced by other organs, especially the heart in the case of TGO. It is therefore important that the evaluation of the examination is carried out by the doctor who requested the examination, since it is possible to check if there has been any change and, if so, be able to establish the cause.
Changes in TGO and PMTct usually indicate liver damage, which can occur due to hepatitis, cirrhosis or the presence of fat in the liver, and these possibilities are considered when much higher levels of TGO and PGD are observed.
On the other hand, when only TGO is altered, for example, there may be a change in the heart, since TGO is also a heart marker. Thus, in this situation, your doctor may indicate tests that evaluate your heart health, such as the measurement of troponin, myoglobin, and creattinophosphokinase (CK). Learn more about TGO.
In general, changes in TGO and TGP levels may be related to the following situations:
Thus, the dosage of these enzymes is requested by the doctor when any of these situations are suspected and when there are evocative symptoms, such as yellow skin and eyes, dark urine, frequent and for no apparent reason, and yellow or whitish stools. Learn about the other symptoms of liver problems.
In addition to evaluating TGO and TGP levels, to confirm liver injury and its extent, the doctor applies the Ritis index, which is the index between TGO and TGP levels and which, when greater than 1, indicates lesions. Treatment should be initiated as soon as possible to prevent disease progression.