Bone marrow aplasia or bone marrow aplasia is a disease characterized by changes in bone marrow function.Bone marrow is responsible for the production of blood cells.When compromised by any factor, its production can be reduced or stopped, leading to low concentrations of red.blood cells, platelets and leukocytes circulating in the blood.
The cause of spinal aplasia is generally unknown, but it may be associated with exposure to chemical agents, radiation, medications, or may be the result of a more serious illness, such as Fanconi anemia.variety of symptoms, such as paleness, shortness of breath, bruising, and frequent infections.
- Treatment is based on the degree of aplasia and is usually done with the use of immunosuppressants.
- Antibiotics.
- Blood transfusions and.
- In the most severe cases.
- Bone marrow transplants.
- Treatment can only be determined by the doctor after the result of the blood count.
- And myelogram.
- Which must be requested by the doctor.
As a disease in which there is a low number of red blood cells, platelets and white blood cells, symptoms of spinal aplasia are related to the decrease of these elements in the blood:
Esses sintomas podem surgir de repente ou de forma mais lenta e gradual. Além disso pode ser que haja dor de cabeça, taquicardia e tontura nos casos de aplasia medular.
Spinal aplasia can be synonymous with aplastic anemia, as both have the same cause, symptoms and treatment.Learn more about aplastic anemia.
Spinal aplasia is not cancer. Although leukemia is a type of cancer that affects blood cells, there is a change in the bone marrow that allows the bone marrow to produce and release more cells from a given cell line or release cells that have not yet experienced a maturation process, such as myelocytes, for example.
In spinal cord aplasia, on the other hand, the bone marrow loses its function, i.e. cells are produced in a much smaller amount or there is simply no production.
Causes of spinal aplasia are not always known, but they are usually related to:
Spinal cord aplasia is rarely hereditary, but when it occurs, it is usually related to Fanconi anemia, which is a serious, genetic and rare disease in which the child has visible defects from birth, skin imperfections, kidney failure, short stature and more.He’s likely to develop tumors and leukemia.
The diagnosis of spinal aplasia is made by a blood test indicated by the family doctor, the blood formula, in which the amounts of red blood cells, leukocytes and platelets circulating in the blood can be checked.
In addition, your doctor may order a myelogram, which is a slightly more invasive test that performs a suction of blood and bone marrow in your hip bone or sternum to check how your blood cells are produced.See what the directions are and how the myelogram is performed.
Treatment of spinal aplasia is based on the degree of aplasia; With proper treatment, the image of spinal aplasia can be reversed, i.e. the bone marrow can regain its ability to produce blood cells, so spinal aplasia is curable.
Treatment of spinal aplasia may be done with
In cases of more severe aplasia, a bone marrow transplant may be necessary, which, despite a high risk of complications, the chance of recovery is greater.See how bone marrow transplants occur.