Parry-Romberg syndrome, or simply Romberg syndrome, is a rare disease characterized by skin atrophy, muscles, fat, bone tissue and facial nerves, resulting in aesthetic deformity; This disease usually affects only one side of the face, however, it can spread to the rest of the body.
This disease is incurable, but medication and surgery help control disease progression.
- The disease usually begins with changes in the face just above the jaw or in the space between the nose and mouth.
- Extending to other areas of the face.
In addition, other signs such as
Over time, Parry-Romberg syndrome can also cause changes within the mouth, especially on the roof of the mouth, inside the cheeks and gums. In some cases, neurological symptoms such as seizures and severe facial pain may occur.
These symptoms can progress from 2 to 10 years, then enter a more stable phase in which no further facial changes appear.
In the treatment of Parry-Romberg syndrome, immunosuppressive drugs such as prednisolone, methotrexate or cyclophosphamide are taken to help fight the disease and reduce symptoms, since the main causes of this syndrome are autoimmune, which means that the cells of the immune system attack the tissues of the face, causing for example deformities.
In addition, it may also be necessary to undergo surgery, mainly to reconstruct the face, by performing fat, muscle or bone grafts. The best time to perform surgery varies from person to person, but it is recommended to perform it after adolescence and when the individual has finished growing.