Thrombophilia is characterized by a propensity to form blood clots, which can cause thrombosis, stroke or pulmonary embolism, for example, blood enzymes responsible for clotting stop working properly, which can be due to several factors, one of which is pregnancy.
Pregnancy is a risk factor for the development of thromboembolic events and can cause symptoms such as swelling, skin changes, placental excretion, preeclampsia, changes in fetal growth, onset of preterm birth or even miscarriage.
- Therefore.
- It is important to provide adequate treatment to avoid complications during pregnancy and prevent bleeding during childbirth.
- Learn more about thrombophilia.
Some of the signs and symptoms that may occur in pregnant women with thrombophilia include swelling, skin changes, placental excretion, preeclampsia, changes in fetal growth, preterm birth or even miscarriage.
Pregnancy induces a physiological state of hypercoagulability and hypofibyrolysis, which usually protects pregnant women from childbirth-related bleeding, however this mechanism can contribute to the development of thrombophilia, increasing the risk of venous thrombosis and obstetric complications.
The risk of thrombosis in pregnant women is 5 to 6 times higher than in non-pregnant women, however, there are other factors that increase the likelihood of developing pregnancy-related thrombosis, such as having a history of venous thrombosis, having advanced maternal disease.obesity or some form of immobilization, for example.
Generally, the treatment and prevention of venous thromboembolism during pregnancy involves the administration of aspirin at a dose of 80 to 100 mg /day, which works by inhibiting platelet aggregation.risk to the baby, the benefits of its use outweigh the potential risks.
In addition, injectable heparin, such as enxaparin, is an anticoagulant widely used for thrombophilia during pregnancy and is a safe drug because it does not cross the placental barrier.Enxaparin should be administered daily, subcutaneously and can be applied by the person himself.
Treatment should be done even after delivery for approximately 6 weeks.
To date, it is not considered justified to make the diagnosis in all women who intend to become pregnant, and screening is selective and is based on personal and family history of thrombosis, as well as reproductive history, such as recurrent miscarriages., severe early preeclampsia or insufficient fetal growth, for example.
In addition, women who have some form of immobility, are over 35 years of age, have a BMI greater than 30, and consume cigarettes frequently, for example, have an increased risk of developing thrombophilia during pregnancy and should therefore be diagnosed.