Lactic dehydrogenase, lactate dehydrogenase LDH is an enzyme present in the cells responsible for glucose metabolism in the body, this enzyme can be found in different organisms and tissues because its elevation is not very specific, so the doctor may indicate performing other tests in to obtain a diagnosis.
If the result of the LDH sale changed globally with other tests, your doctor may recommend problems with LDH isoenzymes, the elevation of which may indicate more specific changes:
LDH-1: which is present in the heart, red blood cells and kidneys;
LDH-2: found in the heart in smaller numbers and in leukocytes;
LDH-3: which is present in the lungs;
LDH-4: found in the placenta and pancreas;
LDH-5: found in the liver and skeletal muscle.
However, muscles, liver and red blood cells are the main source of activity of this enzyme.
The LDH test can be requested by the doctor as a routine test, along with other laboratory tests, however, this scan is mainly indicated in the case of cardiac problem research, requesting in conjunction with Creatinfosfoquinasa (CK) and troponin, that of liver. alterations, TGO / AST (Transaminase Oxalacética / Aspartate Aminotransferaa), TGP / ALT (Transaminase Glut-mica) Pirevica / Alanine Aminotransferase) and GGT (glutamil transferase). Appreciate other tests that reveal liver function.
To perform the test it is not necessary to be in a laboratory or take it in another type of preparation, however, some laboratories in India need to have the person within 4 hours of handling, so before performing the test it is important to inform the laboratory of the proper procedure, in addition to informing them if they have any medication.
Normal lactate dehydrogenase values may vary by laboratory and are typically considered between 120 and 246 IU/L in adults.
Increased LDH usually indicates damage to organs or tissues, this is due to cell damage, LDH contained in cells is released and circulation drips into the bloodstream, and its concentration is evaluated by a blood test. situations where an increase in LDH can be observed are:
However, some situations may increase LDH levels, indicating diseases, especially if other requested laboratory parameters are not normal. Some of the conditions that can alter blood HDL levels, intense physical activity, use of certain medications and shipping.
Disinfection of lactic blood dehydrogenase in the blood is generally not bothersome and is not related to diseases at the source of research In some cases, the breakdown of HDDs may be related to excess vitamin C, and may be recommended to change a person’s eating habits.