Domperidone: what it’s for, how to take it and effects

Domperidone is a medicine used to treat poor digestion, nausea and vomiting in adults and children for periods of less than a week.

This remedy can be found generically or under the trade names Motilium, Peridal or Peridone and is available in tablet form or drinkable suspension, and can be purchased from pharmacies for a price between 6 and 45 reais, depending on the size of the packaging and the pharmaceutical form.

  • This medicine is intended to treat digestion problems often associated with delayed gastric emptying.
  • Gastroesophageal and esophageal reflux.
  • Early satiety.
  • Bloating.
  • Severe abdominal pain.
  • Excessive erudites and intestinal gases.
  • Nausea and vomiting.
  • Heartburn and stomach burns with or without regurgitation.
  • Gastric content.

In addition, it is also indicated in cases of nausea and vomiting of functional, organic, infectious or food origin or induced by radiation therapy or pharmacological treatment.

Domperidone should be taken 15 to 30 minutes before meals and, if necessary, before bedtime.

For adults and adolescents weighing more than 35 kg, a dose of 10 mg, 3 times daily, orally, is recommended and the maximum dose of 40 mg should not be exceeded.

In infants and children under 12 years of age or weighing less than 35 kg, the recommended dose is 0.25 ml / kg body weight, up to 3 times daily, orally.

The most common side effects that can occur during treatment with domperidone are depression, anxiety, decreased sexual appetite, headache, drowsiness, restlessness, diarrhea, rashes, itching, breast augmentation and sensitivity, milk production, absence of menstruation, breast pain and muscle weakness. .

This medicine should not be used in people allergic to any of the components of the formula, prolactinism, severe stomach pain, persistent dark stools, liver disease or those who use certain medications that alter metabolism or alter heart rate, as is the case. itraconazole, ketoconazole, posaconazole, voriconazole, erythromycin, clarithromycin, lithromycin, amironeoda, ritonavir or saquinavir.

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