Cannabidiol oil, also known as CBD oil, is a substance obtained from the Cannabis sativa plant, known as marijuana, which is able to alleviate anxiety symptoms, help with the treatment of insomnia and have benefits in the treatment of epilepsy.
Unlike other marijuana-based drugs, cannabidiol oil does not contain THC, which is the marijuana substance responsible for psychotropic effects, such as loss of consciousness and distortions in time and space, for example. Therefore, cannabidiol oil is more likely to be used in clinical practice. Learn about the other effects of marijuana.
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- More studies are needed to clarify the benefits of CBD oil in each problem as well as the most appropriate concentration.
The action of cannabidiol oil is mainly due to its activity on two receptors present in the body, called CB1 and CB2. CB1 is found in the brain and is linked to the regulation of neurotransmitter release and neuronal activity, while CB2 is present in lymphoid organs, which is responsible for inflammatory and infectious responses.
By acting on the CB1 receptor, cannabidiol is able to prevent excessive neural activity, helping to relax and reduce symptoms associated with anxiety, as well as to regulate pain perception, memory, coordination and cognitive abilities. By acting on the CB2 receptor, cannabidiol helps the process of releasing cytokines by immune system cells, which helps reduce pain and inflammation.
Because of the way CBD oil works in the body, its use can bring health benefits and even be considered in the treatment of certain diseases:
Discover the benefits of cannabidiol in the video below
Despite the indications, mechanism of action, properties and absence of THC concentrations, which could make cannabidiol oil more accepted in the medical and scientific community, the effects of long-term use of this oil have not yet been verified, and more studies are needed to help test the effects of CBD oil on more people.
In 2018, the Food and Drug Administration (FDA) approved the use of a drug, Epidiolex, which consists solely of cannabidiol in the treatment of epilepsy, but ANVISA has so far not positioned itself in relation to the sale of the drug in Brazil.
To date, ANVISA has authorized the marketing of Mevatyl, a cannabidiol-based drug and THC indicated primarily to treat involuntary muscle contractions that occur in multiple sclerosis and whose use should be indicated by the doctor. Learn more about Metavyl and its directions.
Some studies have shown that the side effects of cannabidiol oil are related to misuse of the product, mainly without being indicated by a doctor or increased concentrations, checking for fatigue and excessive sleep, diarrhea, changes in appetite and weight, irritability, diarrhea, vomiting and breathing problems. In addition, doses in children greater than 200 mg of cannabidiol have been found to worsen anxiety-related symptoms, as well as promote increased heart rate and mood swings.
It has also been shown that cannabidiol may interfere with the activity of an enzyme produced by the liver, cytochrome P450, which, among other functions, is responsible for the deactivation of certain drugs and toxins. Therefore, CBD can affect the effects of certain medications, as well as decrease the liver’s ability to break down and eliminate toxins, which can increase the risk of liver toxicity.
In addition, the use of cannabidiol oil is not appropriate for pregnant, planning or breastfeeding women, as CBD has been found to be found to be found to be found in breast milk, in addition to being able to be transmitted to the fetus. during pregnancy.