Um estudo publicado na revista Lancet Respiratory Medicine [1] afirma que o ibuprofeno pode causar um agravamento dos sintomas em pessoas com infecções respiratórias virais agudas, como a COVID-19, originando a dúvida sobre se é seguro usar ibuprofeno no tratamento do novo coronavírus.
According to the WHO, there is still insufficient scientific evidence to confirm this possible worsening of COVID-19 by ibuprofen or other nonsteroidal anti-inflammatory drugs, and therefore these medicines may continue to be used under the direction of the doctor.
- Further studies are currently underway to assess the actual relationship between ibuprofen administration and worsening SARS-CoV-2 (COVID-19) infections.
This same enzyme, ECA2, appears to be one of the entry points of coronavirus viruses to cells, and therefore some scientists hypothesize that if there is also an increase in the expression of this enzyme in humans, especially in the lung, it is possible that the virus will multiply more quickly, causing more severe symptoms.
Since ibuprofen is an anti-inflammatory of the nonsteroidal anti-inflammatory drug class (NSAIDs), it has also been considered that the use of drugs of this class could cause the same worsening of COVID-19 symptoms, but who claims that there is sufficient data to confirm this worsening, both for the use of ibuprofen and for any other type of NSAIDs.
Ideally, anti-inflammatory drugs, especially NSDSDS, should only be used under the direction of a doctor.
Treatment to relieve symptoms of COVID-19, such as fever and general discomfort, should be done with the use of acetaminophen as a first alternative. Learn more about the main symptoms of COVID-19 and what to do if you suspect them.
However, because there is insufficient evidence to contradict the use of ibuprofen or other anti-inflammatory drugs, it can also be used, as long as it is guided by a doctor. Therefore, it is very important to follow the doctor’s recommendations and respect the information contained in the notice.