Bupropion hydrochloride is a drug suitable for people who want to quit smoking, it also helps reduce symptoms of withdrawal syndrome and the desire to smoke, in addition, it can also be used to treat depression.
This medicine requires a prescription and is available under the brand name Zyban, in the GlaxoSmithKline laboratory and in generic form.
- Bupropion is a substance capable of reducing the desire to smoke in people addicted to nicotine.
- As it interacts with two chemicals in the brain that are related to addiction and withdrawal.
- Zyban takes about a week to take effect.
- That the drug needs to reach the necessary levels in the body.
Since bupropion interacts with two depression-related brain chemicals, called norepinephrine and dopamine, it can also be used to treat depression.
The dose varies depending on the purpose of treatment
Zyban should start use while still smoking and a closing date should be set during the second week of treatment.
The normally recommended dose is:
– During the first three days, one 150 mg tablet, once daily
– From the fourth day, a 150 mg tablet, twice daily, at least 8 hours apart and never close to bedtime.
If you progress after 7 weeks, your doctor may consider stopping treatment.
The generally recommended dose for most adults is 1 150 mg tablet a day, however, your doctor may increase the dose to 300 mg a day, if the depression does not improve after several weeks.Doses should be taken at least 8 hours apart.avoiding close hours at bedtime.
The most common side effects that occur when using bupropion hydrochloride are insomnia, headaches, dry mouth and gastrointestinal disorders such as nausea and vomiting.
Less commonly, allergic reactions, loss of appetite, restlessness, anxiety, depression, tremors, dizziness, taste disturbances, difficulty concentrating, abdominal pain, constipation, rash, itching, blurred vision, sweating, fever and weakness.
This medicine is contraindicated in people allergic to one of the components of the formula, who are taking other medicines containing bupropion or who have recently taken tranquilizers, sedatives or monoamine oxidase inhibitors used in depression or Parkinson’s disease.
In addition, it should not be used by people under the age of 18, who have epilepsy or other epileptic disorders, eating disorders, frequent consumption of alcoholic beverages, or who are trying to stop drinking or have recently stopped drinking.