Acitretine (Neotigason)

Neotigason is an antipsyrosis and antidateantatosis drug, which uses acitretin as an active substance, is an oral medicine that is presented in capsules that should not be chewed but always consumed with food.

Severe psoriasis; severe queratinization disorders.

  • Atherosclerosis; dry mouth conjunctivitis; peeling skin decreased night vision joint pain Skull pain; muscle pain bone pain reversible elevations of triglyceride levels and serum cholesterol; transient and reversible elevations of transaminase and alkaline phosphatase; nosebleeds Inflammation of tissues around the nails worsening symptoms of the disease Problems bone loss of pronounced hair cracked lips; brittle nails.

Risk of pregnancy X; Hypersensitivity of breastfeeding to acitretin or retinoids; Severe liver failure Severe kidney failure a woman who is likely to become pregnant with abnormally high levels of blood lipids.

Adults:

Severe psoriasis 25 to 50 mg in a single daily intake, after 4 weeks can reach 75 mg / day. Maintenance: 25 to 50 mg in a single daily intake, up to 75 mg / day.

Severe queratinization disorders: 25 mg in a single daily intake, after 4 weeks can reach 75 mg / day. Maintenance: 1 to 50 mg in one intake.

Elderly patients: may be more sensitive to the usual doses

Children: Severe queratinization disorders: start with 0. 5 mg / kg / weight as a single daily dose, being able to reach 1 mg without exceeding 35 mg / day. Maintenance: 20 mg or less in a single daily intake.

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